3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Base Information

Chemical Name:3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine
CAS No.:205485-24-1
Molecular Formula:C9H7 F3 N2 O
Molecular Weight:216.163
Hs Code.:
DSSTox Substance ID:DTXSID80440364
Nikkaji Number:J576.042I
Mol file:205485-24-1.mol

Synonyms:205485-24-1;3-(3-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-3H-DIAZIRINE;3-(3-methoxyphenyl)-3-(trifluoromethyl)diazirine;3H-Diazirine, 3-(3-methoxyphenyl)-3-(trifluoromethyl)-;3-[3-Methoxyphenyl]-3-(trifluoromethyl)diazirine;SCHEMBL3727466;DTXSID80440364;AKOS028108925;FT-0671353;EN300-9523065;J-013401;3-(Trifluoromethyl)-3-(3-methoxyphenyl)-3H-diazirine

Suppliers and Price of 3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine
50mg
$ 290.00

Medical Isotopes, Inc.
3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine
25 mg
$ 845.00

Crysdot
3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine 97%
100mg
$ 530.00

Crysdot
3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine 97%
250mg
$ 975.00

Chemenu
3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine 97%
250mg
$ 912.00

American Custom Chemicals Corporation
3-(3-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-3H-DIAZIRINE 95.00%
250MG
$ 1871.10

American Custom Chemicals Corporation
3-(3-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-3H-DIAZIRINE 95.00%
25MG
$ 739.20

Total 5 raw suppliers

Chemical Property of 3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Chemical Property:

Boiling Point:233.4±50.0℃ (760 Torr)
Flash Point:94.9±30.1℃
PSA：33.95000
Density:1.39±0.1 g/cm3 (20 ºC 760 Torr)
LogP:1.74730
Storage Temp.:Amber Vial, -20?C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:216.05104734
Heavy Atom Count:15
Complexity:271

Purity/Quality:

98% ^*data from raw suppliers

3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)C2(N=N2)C(F)(F)F

Technology Process of 3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

There total 9 articles about 3-(3-Methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 877667-30-6
2,2,2-trifluoro-1-(3-methoxyphenyl)-N-{[(4-methylphenyl)sulfonyl]oxy}ethanimine

: 205485-24-1
3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Guidance literature:: With lithium amide; ammonia; In diethyl ether; at -78 - 20 ℃; for 9h; Reagent/catalyst; Sealed tube;
DOI:10.1021/ol503630z

Reference yield: 98.0%

: 154187-45-8
3-(3-Methoxyphenyl)-3-(trifluoromethyl)diaziridine

: 205485-24-1
3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Guidance literature:: With silver(l) oxide; In diethyl ether; for 20h; in the dark;
DOI:10.1039/b514205a

Reference yield:

: 30724-22-2
2,2,2-trifluoro-1-(3-methoxyphenyl)ethanone

: 205485-24-1
3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine

Guidance literature:: Multi-step reaction with 4 steps

1: 92 percent / NH₂OH*HCl; C₅H₅N

2: 93 percent / C₅H₅N

3: 88 percent / NH₃

4: 73 percent / I₂; Et₃N / methanol

With pyridine; hydroxylamine hydrochloride; ammonia; iodine; triethylamine; In methanol;
DOI:10.1055/s-2005-923595