tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

Base Information

Chemical Name:tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate
CAS No.:912971-43-8
Molecular Formula:C₂₈H₃₇N₃O₃
Molecular Weight:463.62
Hs Code.:

Synonyms:tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

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Chemical Property of tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

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Technology Process of tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

There total 2 articles about tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 912971-80-3
2-(2-methoxyphenyl)-5-(piperidin-4-yl)-1H-indole

: 123387-72-4
O-tert-butyl N-methyl-N-(2-oxoethyl)carbamate

: 912971-43-8
tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

Guidance literature:: 2-(2-methoxyphenyl)-5-(piperidin-4-yl)-1H-indole; O-tert-butyl N-methyl-N-(2-oxoethyl)carbamate; With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; water; ethyl acetate; Product distribution / selectivity;

Reference yield:

: 912971-35-8
tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl(methyl)carbamate

: 912971-43-8
tert-butyl 2-(4-(2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)ethyl(methyl)carbamate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 6h; under 1551.49 Torr; Product distribution / selectivity;