Technology Process of (R)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-phenyl-propionic acid methyl ester
There total 26 articles about (R)-2-((S)-2-Amino-3-methyl-butyrylamino)-3-phenyl-propionic acid methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; hydrogen;
palladium;
In
methanol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / ethyldiisopropylamine; 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium BF4 / CH2Cl2 / 20 °C
2: 100 percent / trifluoroacetic acid; anisole / CH2Cl2
With
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; methoxybenzene; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid;
In
dichloromethane;
DOI:10.1021/jo061830j
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Et3N, isobutyl chloroformate / tetrahydrofuran / 16 h / Ambient temperature
2: H2 / 5percent Pd/C / methanol / 5 h / Ambient temperature
With
hydrogen; triethylamine; isobutyl chloroformate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol;
