4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Base Information

Chemical Name:4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester
CAS No.:924312-34-5
Molecular Formula:C₁₃H₁₄F₂O₄
Molecular Weight:272.249
Hs Code.:2917399590

Synonyms:4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Suppliers and Price of 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate
5 g
$ 1109.00

Crysdot
Ethyl4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate 97%
5g
$ 465.00

AK Scientific
Ethyl4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate
5g
$ 937.00

Total 2 raw suppliers

Chemical Property of 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

There total 8 articles about 4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 667-27-6
Ethyl bromodifluoroacetate

: 4334-88-7
p-ethoxycarbonylphenylboronic acid

: 924312-34-5
4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Guidance literature:: With [2,2]bipyridinyl; nickel(II) nitrate hexahydrate; potassium carbonate; In 1,4-dioxane; at 60 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1002/anie.201405653

Reference yield: 87.0%

: 667-27-6
Ethyl bromodifluoroacetate

: 51934-41-9
4-iodobenzoic acid ethyl ester

: 924312-34-5
4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; tetrabutylammomium bromide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc; In tetrahydrofuran; at 60 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.orglett.7b00938

Reference yield: 84.0%

: 5798-75-4
Ethyl 4-bromobenzoate

: 667-27-6
Ethyl bromodifluoroacetate

: 924312-34-5
4-(2-ethoxy-1,1-difluoro-2-oxoethyl)benzoic acid ethyl ester

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; tetrabutylammomium bromide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc; In tetrahydrofuran; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1021/acs.orglett.7b00938