diethoxyphosphoryl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]iminoacetate

Base Information

• Chemical Name: diethoxyphosphoryl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]iminoacetate
• CAS No.: 204185-34-2
• Molecular Formula: C15H24 N3 O8 P S
• Molecular Weight: 437.411
• DSSTox Substance ID: DTXSID80445253
• Wikidata: Q82263611
• Mol file: 204185-34-2.mol

Synonyms:

Chemical Property of diethoxyphosphoryl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]iminoacetate

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.56
• Boiling Point: 521.195°C at 760 mmHg
• Flash Point: 269.009°C
• PSA: 186.68000
• Density: 1.402g/cm³
• LogP: 3.09320
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 13
• Exact Mass: 437.10217290
• Heavy Atom Count: 28
• Complexity: 615

Purity/Quality:

98%min ^*data from raw suppliers

PTMA ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=O)(OCC)OC(=O)C(=NOCC(=O)OC(C)(C)C)C1=CSC(=N1)N
• Isomeric SMILES: CCOP(=O)(OCC)OC(=O)/C(=N/OCC(=O)OC(C)(C)C)/C1=CSC(=N1)N

Technology Process of diethoxyphosphoryl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]iminoacetate

There total 1 articles about diethoxyphosphoryl (2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethoxy]iminoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.3%

diethyl chlorophosphate (814-49-3) + (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[[2-(tert-butoxy)-2-oxoethoxy]imino]acetic acid (74440-02-1) → [1-(2-Amino-thiazol-4-yl)-2-(diethoxy-phosphoryloxy)-2-oxo-eth-(Z)-ylideneaminooxy]-acetic acid tert-butyl ester (204185-34-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 5 ℃; for 2h;

DOI:10.1080/00397919808005071

upstream raw materials:

diethyl chlorophosphate

(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[[2-(tert-butoxy)-2-oxoethoxy]imino]acetic acid