(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

Base Information

Chemical Name:(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride
CAS No.:1247029-26-0
Molecular Formula:C₁₃H₁₇F₃N₂O₂S*ClH
Molecular Weight:358.812
Hs Code.:

Synonyms:(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

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Technology Process of (4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

There total 1 articles about (4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1247029-24-8
4-(4-methylsulfonyl-3-trifluoromethyl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

: 1247029-26-0
(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

Guidance literature:: 4-(4-methylsulfonyl-3-trifluoromethyl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

With hydrogenchloride; In 1,4-dioxane;

Reference yield:

: 1247029-26-0
(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride

: 1247029-01-1
4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt

: 1247029-27-1
1-[4-(4-methanesulfonyl-3-trifluoromethyl-phenylamino)-piperidin-1-yl]-4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butan-1-one

Guidance literature:: 4-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-butyric acid lithium salt; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; for 0.0833333h;

(4-methanesulfonyl-3-trifluoromethyl-phenyl)-piperidin-4-yl-amine hydrochloride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 2h;