C₃₂H₃₄O₂Si

Base Information

• Chemical Name: C₃₂H₃₄O₂Si
• CAS No.: 1337556-64-5
• Molecular Formula: C₃₂H₃₄O₂Si
• Molecular Weight: 478.706
• Mol file: 1337556-64-5.mol

Synonyms:C₃₂H₃₄O₂Si

Chemical Property of C₃₂H₃₄O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₂H₃₄O₂Si

There total 5 articles about C₃₂H₃₄O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate (1337556-20-3) → C32H34O2Si (1337556-64-5) + rac-(2S,3R,Z)-2-(tert-butoxycarbonylamino)-4-[(tert-butyldiphenylsilyloxy)methyl]-3,5-diphenylpent-4-enoic acid

Guidance literature:

With sodium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 0.333333h; optical yield given as %de; diastereoselective reaction;

DOI:10.1021/jo201727g

Reference yield:

C16H16O2 + tert-butylchlorodiphenylsilane (58479-61-1) → C32H34O2Si (1337556-64-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 23h; Inert atmosphere;

DOI:10.1021/jo201727g

Reference yield:

ethyl (Z)-2-[hydroxy(phenyl)methyl]-3-iodo-2-propenoate → C32H34O2Si (1337556-64-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: palladium diacetate; sodium carbonate / 1,2-dimethoxyethane; water / 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 1 h / 0 - 10 °C

2.2: 20 h / 20 °C / Saturated solution

3.1: dmap; triethylamine / dichloromethane / 23 h / 0 - 20 °C / Inert atmosphere

With dmap; lithium aluminium tetrahydride; palladium diacetate; sodium carbonate; triethylamine; In tetrahydrofuran; 1,2-dimethoxyethane; diethyl ether; dichloromethane; water; 1.1: Suzuki coupling;

DOI:10.1021/jo201727g

upstream raw materials:

tert-butylchlorodiphenylsilane

(E)-2-[(tert-butyldiphenylsilyloxy)methyl]-1,3-diphenylallyl 2-(tert-butoxycarbonylamino)acetate

ethyl (2Z)-2-(1-hydroxy-1-phenylmethyl)-3-phenylacrylate

benzaldehyde