N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide

Base Information

• Chemical Name: N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide
• CAS No.: 473465-11-1
• Molecular Formula: C₁₈H₁₈N₂O₃S
• Molecular Weight: 342.419
• Mol file: 473465-11-1.mol

Synonyms:N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide

Chemical Property of N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide

Chemical Property:

• Boiling Point: 474.9±55.0 °C(Predicted)
• Density: 1.225±0.06 g/cm3(Predicted)

Purity/Quality:

NLT 98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide

There total 1 articles about N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

ethylamine (75-04-7,85404-22-4) + 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonyl chloride (509074-26-4) → N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide (473465-11-1)

Guidance literature:

In dichloromethane; at 0 - 5 ℃; for 2h;

Reference yield:

N-ethyl-[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonamide (473465-11-1) → N-ethyl-4-(5-methyl-3-phenylisoxazol-4-yl)-N-propionylbenzenesulfonamide (473465-00-8)

Guidance literature:

With sulfuric acid; In propionic acid anhydride;

upstream raw materials:

ethylamine

4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonyl chloride

Downstream raw materials:

N-ethyl-4-(5-methyl-3-phenylisoxazol-4-yl)-N-propionylbenzenesulfonamide