ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

Base Information

• Chemical Name: ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside
• CAS No.: 197853-39-7
• Molecular Formula: C₂₆H₄₀O₇S
• Molecular Weight: 496.665

Synonyms:ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

Chemical Property of ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

There total 7 articles about ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

(S)-(+)-2-methylbutyric anhydride (84131-91-9) + ethyl 3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside (179337-13-4) → ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside (197853-39-7)

Guidance literature:

With pyridine; dmap; for 27h; Ambient temperature;

DOI:10.1002/anie.199723441

Reference yield:

ethyl 1-thio-α-L-rhamnopyranoside (127753-94-0) → ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside (197853-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Bu₂SnO; 4 Angstroem molecular sieves / toluene / 1 h / Heating

1.2: 79 percent / CsF; Bu₄NI / dimethylformamide / 33 h / 20 °C

2.1: 69.7 percent / DMAP; pyridine / 27 h / 20 °C

With pyridine; dmap; 4 A molecular sieve; di(n-butyl)tin oxide; In toluene; 1.1: stannylation / 1.2: Alkylation / 2.1: Acylation;

DOI:10.1021/jo9711450

Reference yield:

p-methoxybenzyl chloride (824-94-2) → ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside (197853-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Bu₂SnO; 4 Angstroem molecular sieves / toluene / 1 h / Heating

1.2: 79 percent / CsF; Bu₄NI / dimethylformamide / 33 h / 20 °C

2.1: 69.7 percent / DMAP; pyridine / 27 h / 20 °C

With pyridine; dmap; 4 A molecular sieve; di(n-butyl)tin oxide; In toluene; 1.1: stannylation / 1.2: Alkylation / 2.1: Acylation;

DOI:10.1021/jo9711450

upstream raw materials:

(S)-(+)-2-methylbutyric anhydride

ethyl 3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

ethyl 1-thio-α-L-rhamnopyranoside

p-methoxybenzyl chloride

Downstream raw materials:

ethyl O-[2,3,4-tri-O-benzyl-α-L-rhamnopyranosyl]-(1->3)-2,4-di-O-[2(S)-methylbutyryl]-1-thio-α-L-rhamnopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 197853-39-7 ethyl 2,4-di-O-[2(S)-methylbutyryl]-3-O-(p-methoxybenzyl)-1-thio-α-L-rhamnopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send