(2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol

Base Information

• Chemical Name: (2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol
• CAS No.: 1236279-05-2
• Molecular Formula: C₂₃H₄₀O₃Si
• Molecular Weight: 392.654
• Mol file: 1236279-05-2.mol

Synonyms:(2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol

Chemical Property of (2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol

There total 1 articles about (2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C23H39IO3Si (1236279-04-1) → (2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol (1236279-05-2)

Guidance literature:

With sodium hydrogencarbonate; zinc; In ethanol; for 2h; Reflux;

DOI:10.1055/s-0029-1219810

Reference yield: 98.0%

(2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol (1236279-05-2) + methyl iodide (74-88-4) → C24H42O3Si (1236279-14-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 6h;

DOI:10.1055/s-0029-1219810

Reference yield:

(2S,3R,4R,5R)-1-(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2,4-dimethyloct-7-en-3-ol (1236279-05-2) → C17H26O3

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

DOI:10.1055/s-0029-1219810

upstream raw materials:

C₂₃H₃₉IO₃Si

Downstream raw materials:

C₂₄H₄₂O₃Si