(E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

Base Information

Chemical Name:(E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine
CAS No.:1448169-49-0
Molecular Formula:C₂₇H₂₀F₃N
Molecular Weight:415.458
Hs Code.:

Synonyms:(E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

Suppliers and Price of (E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

Chemical Property:

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Technology Process of (E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

There total 2 articles about (E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 365-06-0
3'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

: 501-65-5
diphenyl acetylene

: 1448169-49-0
(E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

Guidance literature:: With dichloro(benzene)ruthenium(II) dimer; silver hexafluoroantimonate; acetic acid; In 1,4-dioxane; at 80 ℃; for 5h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol401779h

Reference yield:

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 615-36-1
2-bromoaniline

: 1448169-49-0
(E)-2'-(1,2-diphenylethenyl)-5'-(trifluoromethyl)[1,1'-biphenyl]-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / N,N-dimethyl-formamide; water / 24 h / 80 °C / Inert atmosphere

2: dichloro(benzene)ruthenium(II) dimer; silver hexafluoroantimonate; acetic acid / 1,4-dioxane / 5 h / 80 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; dichloro(benzene)ruthenium(II) dimer; silver hexafluoroantimonate; potassium carbonate; acetic acid; In 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1021/ol401779h