diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate

Base Information

• Chemical Name: diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate
• CAS No.: 1113027-30-7
• Molecular Formula: C₃₈H₄₇N₆O₆P
• Molecular Weight: 714.802
• Mol file: 1113027-30-7.mol

Synonyms:diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate

Chemical Property of diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate

There total 1 articles about diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

diisopropyl (2,3-dideoxy-5-O-dimethoxytrityl-1-O-methanesulfonyl-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethyl)phosphonate (1113027-15-8) + adenine (66224-66-6,66224-67-7,66224-68-8,66224-69-9,134434-48-3,134434-49-4,134454-76-5,134461-75-9) → diisopropyl 1-(adenin-9-yl)-5-O-dimethoxytrityl-1,2,3-trideoxy-3-aza-4a-carba-β-L-glycero-pentofuranos-3-ylmethylphosphonate (1113027-30-7)

Guidance literature:

adenine; With caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 0.333333h;

diisopropyl (2,3-dideoxy-5-O-dimethoxytrityl-1-O-methanesulfonyl-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethyl)phosphonate; In N,N-dimethyl-formamide; at 110 ℃; for 4h;

DOI:10.1016/j.tet.2008.11.035

upstream raw materials:

diisopropyl (2,3-dideoxy-5-O-dimethoxytrityl-1-O-methanesulfonyl-3-aza-4a-carba-α-L-glycero-pentofuranos-3-ylmethyl)phosphonate

adenine