5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid

Base Information

Chemical Name:5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid
CAS No.:201349-60-2
Molecular Formula:C₁₅H₁₀O₃
Molecular Weight:238.243
Hs Code.:2932190090
DSSTox Substance ID:DTXSID10699449
Wikidata:Q82630375
Mol file:201349-60-2.mol

Synonyms:5-(4-aminonaphthalen-1-yl)furan-2-carboxylic acid;DTXSID10699449;5-(4-AMINONAPHTHALEN-1-YL)-FURAN-2-CARBOXYLIC ACID

Suppliers and Price of 5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Naphthalen-1-yl)furan-2-carboxylicacid 95+%
1g
$ 518.00

Chemenu
5-(naphthalen-1-yl)furan-2-carboxylicacid 95%
1g
$ 489.00

Total 5 raw suppliers

Chemical Property of 5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid

Chemical Property:

Boiling Point:432.9±33.0 °C(Predicted)
PKA:3.15±0.10(Predicted)
PSA：76.46000
Density:1.293±0.06 g/cm3(Predicted)
LogP:3.96140
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:253.07389321
Heavy Atom Count:19
Complexity:346

Purity/Quality:

97% ^*data from raw suppliers

5-(Naphthalen-1-yl)furan-2-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC=C2N)C3=CC=C(O3)C(=O)O

Technology Process of 5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid

There total 5 articles about 5-(4-Aminonaphthalen-1-yl)furan-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 51792-36-0
5-(naphthalen-1-yl)furan-2-carbaldehyde

: 201349-60-2
5-(naphthalen-1-yl)furan-2-carboxylic acid

Guidance literature:: With silver nitrate; sodium hydroxide; In ethanol; water; for 2h; Heating;
DOI:10.1021/acs.jmedchem.1c01810

Reference yield:

: 854401-91-5
methyl 5-(naphthalen-1-yl)furan-2-carboxylate

: 201349-60-2
5-(naphthalen-1-yl)furan-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In N,N-dimethyl acetamide; at 150 ℃; for 20h; Inert atmosphere;
DOI:10.1002/ejoc.201101102

Reference yield:

: 611-13-2
2-furoic acid methyl ester

: 90-11-9
1-Bromonaphthalene

: 201349-60-2
5-(naphthalen-1-yl)furan-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium acetate; palladium diacetate / N,N-dimethyl acetamide / 20 h / 130 °C / Inert atmosphere

2: potassium hydroxide / N,N-dimethyl acetamide / 20 h / 150 °C / Inert atmosphere

With potassium acetate; palladium diacetate; potassium hydroxide; In N,N-dimethyl acetamide;
DOI:10.1002/ejoc.201101102