3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

Base Information

Chemical Name:3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine
CAS No.:875340-30-0
Molecular Formula:C₁₇H₁₃FN₄OS
Molecular Weight:340.381
Hs Code.:

Synonyms:3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

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Chemical Property of 3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

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Technology Process of 3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

There total 2 articles about 3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 875340-30-0
3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

Guidance literature:

Reference yield: 52.0%

: 7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine

: 875340-30-0
3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

Guidance literature:: 7-(2-Fluoro-4-nitrophenoxy)-2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridine; With sodium tetrahydroborate; nickel dichloride; In tetrahydrofuran; methanol; at 0 ℃; for 0.5h;

With hydrogenchloride; water; In tetrahydrofuran; methanol;

With ammonia; In tetrahydrofuran; methanol; water; pH=~ 11;

Reference yield: 55.0%

: 875340-30-0
3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine

: 4843-06-5
2-(2-methoxyphenyl)carbamoylacetic acid

: N₁-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N₃-(2-methoxyphenyl)malonamide

Guidance literature:: 3-fluoro-4-(2-(1-methyl-1H-imidazol-2-yl)thieno[3,2-b]pypyridin-7-yloxy)benzenamine; 2-(2-methoxyphenyl)carbamoylacetic acid; With benzotriazol-1-ol; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 4h;