4843-06-5

Basic information

• Product Name: Propanoic acid, 3-[(2-methoxyphenyl)amino]-3-oxo-
• Synonyms: Malonsaeure-mono-o-anisidid;N-(2-Methoxy-phenyl)-malonsaeure-monoamid;N-(2-methoxy-phenyl)-malonamic acid;3-(2-methoxyphenylamino)-3-oxopropanoic acid;N-(2-Methoxy-phenyl)-malonamidsaeure
• CAS NO: 4843-06-5
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Mol File: 4843-06-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-[(2-methoxyphenyl)amino]-3-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-[(2-methoxyphenyl)amino]-3-oxo-(4843-06-5)
• EPA Substance Registry System: Propanoic acid, 3-[(2-methoxyphenyl)amino]-3-oxo-(4843-06-5)

Safety Data

• Hazardous Substances Data: 4843-06-5(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 90-04-0 2-methoxy-phenylamine 
• 63631-11-8 C₁₁H₁₃NO₄ 

Downstream Products

• 3148-24-1 folimine 
• 64190-94-9 8-methoxy-N-methylflindersine 
• 90475-69-7 3,3-Dichloro-8-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

An alternative way to analogues of avenanthramides and their antiradical activity

Abstract: The paper is devoted to the synthesis of arylidene malonic acid monoanilides and cinnamoyl anilines by condensation of malonic acid monoanilides with aromatic aldehydes. The presented synthetic route applies simple, cheap, and commercially available aromatic aldehydes and amines, thus overcoming traditional schemes, which involve derivatives of hydroxycinnamic acids. Besides, a mild and effective pyridine-mediated decarboxylation of carboxylic group at Csp2 in arylidene malonic acid monoanilides leading to cinnamoyl anilines is presented. The structures of obtained selected arylidene derivatives were approved additionally by X-ray analysis. The antiradical properties (2,2-diphenyl-1-picrylhydrazyl and galvinoxyl tests) and structure–activity relationships of the synthesized compounds were studied. Graphical abstract: [Figure not available: see fulltext.].

Inhibitors of VEGF receptor and HGF receptor signaling

The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions

Synthesis of Swietenidin-A Methyl Ether

Swietenidin-A methyl ether has been synthesised starting from o-anisidine and diethyl malonate