(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

Base Information

Chemical Name:(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide
CAS No.:1068601-45-5
Molecular Formula:C₂₃H₂₉NO₂
Molecular Weight:351.489
Hs Code.:

Synonyms:(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

Suppliers and Price of (2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

There total 1 articles about (2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1068601-03-5
(R)-N-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]-N,2'-dimethylpent-4-enamide

: 100-39-0
benzyl bromide

: 1068601-45-5
(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

Guidance literature:: (R)-N-[(1S,2S)-1-hydroxy-1-phenylpropan-2-yl]-N,2'-dimethylpent-4-enamide; With n-butyllithium; diisopropylamine; lithium chloride; In tetrahydrofuran; hexane; at -78 - 0 ℃; Inert atmosphere;

benzyl bromide; With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; In tetrahydrofuran; hexane; at -40 ℃; for 1.25h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1021/ja806021y

Reference yield: 91.0%

: 1068601-45-5
(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

: (2R)-2-benzyl-2-methylpent-4-enoic acid

Guidance literature:: With tetra(n-butyl)ammonium hydroxide; water; In 1,4-dioxane; at 115 ℃; for 15h; Inert atmosphere;
DOI:10.1021/ja806021y

Reference yield:

: 358-23-6
trifluoromethylsulfonic anhydride

: 1068601-45-5
(2R)-2-benzyl-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N,2-dimethylpent-4-enamide

: 2-(1-benzyl-1-methyl-but-3-enyl)-3,4-dimethyl-5-phenyl-4,5-dihydro-oxazol-3-ium; trifluoro-methanesulfonate

Guidance literature:: With pyridine; In dichloromethane; at 0 ℃; for 0.166667h; optical yield given as %de; Inert atmosphere;
DOI:10.1021/ja806021y