2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane

Base Information

• Chemical Name: 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane
• CAS No.: 1268690-73-8
• Molecular Formula: C₂₅H₃₂O₅
• Molecular Weight: 412.526
• Mol file: 1268690-73-8.mol

Synonyms:2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane

Chemical Property of 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane

There total 2 articles about 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-3(2H)-furanone (3511-32-8) + 3,5-di-t-butyl-4-hydroxybenzaldehyde (1620-98-0) → 2-(3,5-di-tert-butyl-4-hydroxy-benzylidene)-5-methyl-furan-3-one + 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane (1268690-73-8)

Guidance literature:

5-methyl-3(2H)-furanone; 3,5-di-t-butyl-4-hydroxybenzaldehyde; With tri-sec-butylborate; In dichloromethane; at 0 - 5 ℃; for 2h;

With N-butylamine; In dichloromethane; at 0 - 20 ℃;

With acetic acid; In dichloromethane; at 60 ℃; for 0.5h;

Reference yield:

acetylacetone (123-54-6,81235-32-7) → 2-(3,5-di-tert-butyl-4-hydroxy-benzylidene)-5-methyl-furan-3-one + 2-[bis-(3-keto-5-methylfuranyl)]-3,5-di-tert-butyl-4-hydroxyphenylmethane (1268690-73-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bromine / acetic acid / 1.08 h / 20 °C

2.1: potassium carbonate / dichloromethane / 0.67 h

3.1: tri-sec-butylborate / dichloromethane / 2 h / 0 - 5 °C

3.2: 0 - 20 °C

3.3: 0.5 h / 60 °C

With tri-sec-butylborate; bromine; potassium carbonate; In dichloromethane; acetic acid;

upstream raw materials:

5-methyl-3(2H)-furanone

3,5-di-t-butyl-4-hydroxybenzaldehyde

acetylacetone