5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

Base Information

Chemical Name:5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester
CAS No.:435333-72-5
Molecular Formula:C₃₆H₃₆N₂O₁₃S
Molecular Weight:736.753
Hs Code.:

5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

Synonyms:5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

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Chemical Property of 5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

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Technology Process of 5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

There total 4 articles about 5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95877-09-1
2-cyano-3-(4-hydroxy-3-methoxyphenyl)prop-2-enethioamide

: 435333-72-5
5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / piperidine / ethanol / 6 h / Heating

2: aq. KOH / acetone

With piperidine; potassium hydroxide; In ethanol; acetone;
DOI:10.1016/S0040-4020(01)01242-X

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 435333-72-5
5-Cyano-4-(4-hydroxy-3-methoxy-phenyl)-2-phenyl-6-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-nicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / piperidine / ethanol / 6 h / Heating

2: aq. KOH / acetone

With piperidine; potassium hydroxide; In ethanol; acetone;
DOI:10.1016/S0040-4020(01)01242-X