Technology Process of C23H20ClFN4O
There total 6 articles about C23H20ClFN4O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
at 23 ℃;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium nitrite; toluene-4-sulfonic acid; potassium iodide / water; acetonitrile / 4.17 h / 10 - 20 °C
2: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene; zinc / N,N-dimethyl acetamide / 15 h / 120 °C / Inert atmosphere
3: water; sodium hydroxide / tetrahydrofuran / 15 h / 23 °C
4: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / 23 °C
With
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); water; benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium iodide; sodium hydroxide; zinc; sodium nitrite;
In
tetrahydrofuran; N,N-dimethyl acetamide; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: palladium 10% on activated carbon; hydrogen / ethanol; tetrahydrofuran / 6 h
2: sodium nitrite; toluene-4-sulfonic acid; potassium iodide / water; acetonitrile / 4.17 h / 10 - 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); 1,1'-bis-(diphenylphosphino)ferrocene; zinc / N,N-dimethyl acetamide / 15 h / 120 °C / Inert atmosphere
4: water; sodium hydroxide / tetrahydrofuran / 15 h / 23 °C
5: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / 23 °C
With
1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); palladium 10% on activated carbon; water; hydrogen; benzotriazol-1-ol; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium iodide; sodium hydroxide; zinc; sodium nitrite;
In
tetrahydrofuran; ethanol; N,N-dimethyl acetamide; water; acetonitrile;