N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

Base Information

Chemical Name:N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide
CAS No.:850536-52-6
Molecular Formula:C₂₉H₃₀N₂O
Molecular Weight:422.57
Hs Code.:

Synonyms:N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

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Chemical Property of N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

There total 1 articles about N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 502694-01-1
(S)-N-benzylidene-1-(1-napthyl)ethylamine

: (R)-N-methyl-N-(1-phenylethyl)-1-(trimethylsilyl)methanamide

: 850536-52-6
N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

: N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

Guidance literature:: (S)-N-benzylidene-1-(1-napthyl)ethylamine; (R)-N-methyl-N-(1-phenylethyl)-1-(trimethylsilyl)methanamide; With boron trifluoride diethyl etherate; In benzene; for 40h;

With water;
DOI:10.1016/j.tetasy.2005.01.025

Reference yield: 80.0%

: 850536-52-6
N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

: 850629-08-2
2-amino-N-methyl-2-phenyl-N-(1-phenyl-ethyl)-acetamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 25 ℃; for 10h; under 760 Torr;
DOI:10.1016/j.tetasy.2005.01.025

Reference yield:

: 850536-52-6
N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide

: 63291-39-4
(R)-phenylglycine amide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / hydrogen / Pd/C / methanol / 10 h / 25 °C / 760 Torr

2: 75 percent / HCl / H₂O / 20 h / 110 °C

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; water;
DOI:10.1016/j.tetasy.2005.01.025