63291-39-4

Usage

Chemical Properties

White powder

InChI:InChI=1/C8H10N2O.ClH/c9-7(8(10)11)6-4-2-1-3-5-6;/h1-5,7H,9H2,(H2,10,11);1H/t7-;/m1./s1

Upstream product

• 51703-58-3 (RS)-phenylglycinamide hydrochloride 
• 700-63-0 (R)-phenylglycine amide 
• 502694-01-1 (S)-N-benzylidene-1-(1-napthyl)ethylamine 
• 850536-52-6 N-methyl-N-[(R)-1-phenylethyl]-2-phenyl-2-{N-[(S)-1-(1-naphthyl)ethyl]amino}ethanamide 
• 850629-08-2 2-amino-N-methyl-2-phenyl-N-(1-phenyl-ethyl)-acetamide 

Downstream Products

• 1299492-07-1 2-[1-(S)-cyano-2-(4-methoxyphenyl)-1-methylethylamino]-2-(R)-phenylacetamide 
• 103-81-1 Benzeneacetamide 
• 1299492-08-2 2-[(R)-(carbamoylphenylmethyl)-amino]-3-(4-methoxyphenyl)-2-(S)-methylpropionamide 

Relevant academic research and scientific papers

Diastereoselective formation of α-aminoamides from carbamoylsilanes and aldehyde imines

Diastereoselectivities were determined for the reaction of a series of aldehyde imines with carbamoylsilanes, each containing chiral auxiliaries at nitrogen. A maximum de of 88% was achieved via a matched double differentiation.

STEREOSELECTIVE SYNTHESIS OF METYROSINE

Provided herein are compositions including diastereomers in substantially diastereomerically pure form and enantiomers in substantially enantiomerically pure form, and processes for preparing them and converting them to metyrosine.

COMPOSITIONS AND METHODS FOR CYCLOFRUCTANS AS SEPARATION AGENTS

The present invention relates to derivatized cyclofructan compounds, compositions comprising derivatized cyclofructan compounds, and methods of using compositions comprising derivatized cyclofructan compounds for chromatographic separations of chemical species, including enantiomers. Said compositions may comprise a solid support and/or polymers comprising derivatized cyclofructan compounds.