5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid

Base Information

• Chemical Name: 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid
• CAS No.: 1392196-82-5
• Molecular Formula: C₂₁H₂₅BrN₂O₄
• Molecular Weight: 449.344
• Mol file: 1392196-82-5.mol

Synonyms:5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid

Chemical Property of 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid

There total 4 articles about 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

4-(8-bromooctyloxy)aniline (1392196-81-4) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid (1392196-82-5)

Guidance literature:

4-(8-bromooctyloxy)aniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃; for 0.333333h;

salicylic acid; With sodium hydroxide; In water; at 0 - 20 ℃; for 0.5h; pH=12 - 14;

DOI:10.1021/ml300086c

Reference yield:

1-((8-bromooctyl)oxy)-4-nitrobenzene (88138-53-8) → 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid (1392196-82-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 10% Pd/C; hydrogen / ethanol / 3 h / 2068.65 Torr

2.1: hydrogenchloride; sodium nitrite / water / 0.33 h / 0 °C

2.2: 0.5 h / 0 - 20 °C / pH 12 - 14

With hydrogenchloride; 10% Pd/C; hydrogen; sodium nitrite; In ethanol; water;

DOI:10.1021/ml300086c

Reference yield:

1,8-dibromooctane (4549-32-0) → 5-((4-(8-bromooctyloxy)phenyl)diazenyl)-2-hydroxybenzoic acid (1392196-82-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / acetone / 12 h / Reflux

2.1: 10% Pd/C; hydrogen / ethanol / 3 h / 2068.65 Torr

3.1: hydrogenchloride; sodium nitrite / water / 0.33 h / 0 °C

3.2: 0.5 h / 0 - 20 °C / pH 12 - 14

With hydrogenchloride; 10% Pd/C; hydrogen; potassium carbonate; sodium nitrite; In ethanol; water; acetone;

DOI:10.1021/ml300086c

upstream raw materials:

1,8-dibromooctane

4-(8-bromooctyloxy)aniline

salicylic acid

1-((8-bromooctyl)oxy)-4-nitrobenzene