4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

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Chemical Name:4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol
CAS No.:1442371-70-1
Molecular Formula:C₂₉H₃₃N₇O₂S
Molecular Weight:543.693
Hs Code.:

Synonyms:4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

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Chemical Property of 4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

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Technology Process of 4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

There total 6 articles about 4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 1442371-90-5
10-(2-{[tert-butyl(diphenyl)silyl]oxy}-4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]butyl)-2-(4-methylpiperazin-1-yl)-10H-phenothiazine

: 1442371-70-1
4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2013.04.034

Reference yield: 49.0%

: 1401710-56-2
10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(4-methylpiperazin-1-yl)-10H-phenothiazine

: 1442371-70-1
4-[2-(4-methoxyphenyl)-2H-tetrazol-5-yl]-1-[2-(4-methylpiperazin-1-yl)-10H-phenothiazin-10-yl]butan-2-ol

Guidance literature:: 10-((1E,3Z)-4-(2-(4-methoxyphenyl)-2H-tetrazol-5-yl)buta-1,3-dien-1-yl)-2-(4-methylpiperazin-1-yl)-10H-phenothiazine; With dimethylsulfide borane complex; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

With dihydrogen peroxide; sodium hydroxide; In methanol; water; at 0 - 20 ℃; for 24h;
DOI:10.1016/j.bmc.2013.04.034