Technology Process of C18H28O2Si
There total 5 articles about C18H28O2Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(S)-tert-butyldimethyl(5-phenylpent-1-yn-3-yloxy)silane;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.5h;
formaldehyd;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
With
water; ammonium chloride;
In
tetrahydrofuran; hexane;
DOI:10.1021/ol800300x
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
2.1: 1H-imidazole / dichloromethane / 12 h / 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
3.2: 5 h / -78 - 20 °C
With
1H-imidazole; n-butyllithium;
In
tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.201200809
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate / dichloromethane / 4 h / -20 °C / Inert atmosphere
2.1: tetrachloromethane; triphenylphosphine / dichloromethane / 6 h / Inert atmosphere; Reflux
3.1: n-butyllithium / tetrahydrofuran / 2 h / -78 °C / Inert atmosphere
4.1: 1H-imidazole / dichloromethane / 12 h / 20 °C / Inert atmosphere
5.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
5.2: 5 h / -78 - 20 °C
With
1H-imidazole; titanium(IV) isopropylate; tert.-butylhydroperoxide; tetrachloromethane; n-butyllithium; L-(+)-diisopropyl tartrate; triphenylphosphine;
In
tetrahydrofuran; dichloromethane;
1.1: Sharpless epoxidation;
DOI:10.1002/anie.201200809
