CIS-DECAHYDROISOQUINOLINE

Base Information

• Chemical Name: CIS-DECAHYDROISOQUINOLINE
• CAS No.: 2744-08-3
• Molecular Formula: C₉H₁₇N
• Molecular Weight: 139.241
• Mol file: 2744-08-3.mol

Synonyms:Isoquinoline,decahydro-, cis- (8CI); cis-Decahydroisoquinoline; cis-Perhydroisoquinoline;rel-(4aS,8aS)-1,2,3,4,4a,5,6,7,8,8a-Decahydroisoquinoline

Chemical Property of CIS-DECAHYDROISOQUINOLINE

Chemical Property:

• PSA: 12.03000
• Density: 0,95 g/cm3
• LogP: 2.11490

Purity/Quality:

>99% ^*data from raw suppliers

cis-Decahydroisoquinoline ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (4aR,8aR)-Decahydroisoquinoline is a synthetic building block predominately used in the synthesis of natural products.

Technology Process of CIS-DECAHYDROISOQUINOLINE

There total 35 articles about CIS-DECAHYDROISOQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

→ decahydroisoquinoline (2744-08-3,2744-09-4,6329-61-9)

Guidance literature:

Reference yield: 69.4%

quinoline (91-22-5) → decahydroisoquinoline (2744-08-3,2744-09-4,6329-61-9) + 1,2,3,4-tetrahydroisoquinoline (635-46-1) + decahydroquinoline (767-92-0,10343-99-4,22160-37-8,22160-38-9,105728-23-2,115730-30-8,115730-31-9,150254-00-5,2051-28-7)

Guidance literature:

With hydrogen; In ethanol; at 100 ℃; for 1h; under 37503.8 Torr; Temperature; Catalytic behavior; Autoclave;

DOI:10.1016/j.jallcom.2020.155203

Reference yield: 32.5%

quinoline (91-22-5) → decahydroisoquinoline (2744-08-3,2744-09-4,6329-61-9) + 1,2,3,4-tetrahydroisoquinoline (635-46-1)

Guidance literature:

With hydrogen; In ethanol; at 100 ℃; for 1h; under 37503.8 Torr; Catalytic behavior; Autoclave;

DOI:10.1016/j.jallcom.2020.155203

upstream raw materials:

isoquinoline

1,2,3,4-tetrahydroisoquinoline

N-ethoxycarbonyl-cis-decahydroisoquinoline

(4aS^*,8aS^*)-1,2,3,4,4a,5,6,7,8,8a-perhydroisoquinoline-1,3-dione

Downstream raw materials:

isoquinoline

5,6,7,8-tetrahydroisoquinoline

1,2,3,4-tetrahydroisoquinoline

(4aS^*,8aS^*)-1,2,3,4,4a,5,6,7,8,8a-perhydroisoquinoline

Refernces

• 1、 Okazaki,Soeda,Ikefuji,Tamura,Mochida. "Kinetic study on hydrogenation of isoquinoline over supported ruthenium catalysts". . p. 3622 - 3627. Retrieved 1989.
• 2、 Chen, Bing Hui,Liao, Jianhua,Pei, An,Ruan, Luna,Wang, Jiexiang,Yang, Kai,Zhang, Huan,Zhu, Lihua. "PtRuNi/C novel nanostructures of platinum-ruthenium island-on-Ni/Ni(OH)2 nanoparticles for the selective hydrogenation of quinoline". . . Retrieved 2020/04/27.
• 3、 -. "PEPTIDE COMPOUNDS DERIVED FROM BORONIC ACID". . . Retrieved 2008/06/13.