N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide

Base Information

• Chemical Name: N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide
• CAS No.: 1454909-12-6
• Molecular Formula: C₃₈H₃₆NO₃P
• Molecular Weight: 585.683
• Mol file: 1454909-12-6.mol

Synonyms:N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide

Chemical Property of N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide

There total 2 articles about N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4,4'-dimethoxydiphenylacetylene (2132-62-9) + N-phenyl-P,P-bis(3,5-dimethylphenyl)phosphinic amide (1454907-93-7) → N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide (1454909-12-6)

Guidance literature:

With potassium dihydrogenphosphate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate; In tert-butyl alcohol; for 30h;

Reference yield:

ethyl bis(3,5-dimethylphenyl)phosphinate (1454908-01-0) + aniline (62-53-3) → N-phenyl-1-(3,5-dimethylphenyl)-3,4-di(p-methoxyphenyl)-1,2-dihydro-5,7-dimethylbenz[c-1,2]azaphosphinine 1-oxide (1454909-12-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trichlorophosphate; phosphorus pentachloride / 4 h / 0 - 110 °C / Inert atmosphere

1.2: 1 h / 50 °C

2.1: silver carbonate; potassium dihydrogenphosphate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; oxygen / tert-butyl alcohol / 16 h / 110 °C

With potassium dihydrogenphosphate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; phosphorus pentachloride; oxygen; silver carbonate; trichlorophosphate; In tert-butyl alcohol;

DOI:10.1039/c3cc44995e

upstream raw materials:

ethyl bis(3,5-dimethylphenyl)phosphinate

aniline

4,4'-dimethoxydiphenylacetylene

N-phenyl-P,P-bis(3,5-dimethylphenyl)phosphinic amide