C₃₃H₃₉F₃N₆OS

Base Information

Chemical Name:C₃₃H₃₉F₃N₆OS
CAS No.:1432488-16-8
Molecular Formula:C₃₃H₃₉F₃N₆OS
Molecular Weight:624.773
Hs Code.:

C<sub>33</sub>H<sub>39</sub>F<sub>3</sub>N<sub>6</sub>OS

Synonyms:C₃₃H₃₉F₃N₆OS

Suppliers and Price of C₃₃H₃₉F₃N₆OS

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₃₃H₃₉F₃N₆OS

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₃₃H₃₉F₃N₆OS

There total 10 articles about C₃₃H₃₉F₃N₆OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 2290-65-5
trimethylsilyl isothiocyanate

: 1432488-15-7
1-((5-(((2-(diethylamino)ethyl)(methyl)amino)methyl)-1-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)-1H-imidazol-2-yl)methyl)-2-thioxo-2,3,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-4(5H)-one

: 1432488-16-8
C₃₃H₃₉F₃N₆OS

Guidance literature:: In N,N-dimethyl-formamide; at 140 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2013.03.062

Reference yield:

: 312936-77-9
1-(4-Bromobenzyl)-2-Mercapto-5-Hydroxymethylimidazole

: 1432488-16-8
C₃₃H₃₉F₃N₆OS

Guidance literature:: Multi-step reaction with 9 steps

1: dihydrogen peroxide; acetic acid / dichloromethane / 0.33 h / 35 °C

2: caesium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 12 h / Reflux; Inert atmosphere

3: manganese(IV) oxide / 1,4-dioxane / 3 h / 60 °C

4: 1,4-dioxane / 36 h

5: sodium tris(acetoxy)borohydride / dichloromethane / 2 h / 20 °C

6: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 3 h / Reflux

7: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 760.05 Torr

8: tetraethoxy orthosilicate / 3 h / Reflux

9: N,N-dimethyl-formamide / 140 °C / Inert atmosphere

With manganese(IV) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetraethoxy orthosilicate; palladium 10% on activated carbon; diphenylphosphoranyl azide; hydrogen; dihydrogen peroxide; sodium tris(acetoxy)borohydride; caesium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.03.062

Reference yield:

: 106-40-1
4-bromo-aniline

: 1432488-16-8
C₃₃H₃₉F₃N₆OS

Guidance literature:: Multi-step reaction with 10 steps

1.1: hydrogenchloride / acetonitrile / 0.05 h / Cooling with ice

1.2: 2 h / 70 °C

2.1: dihydrogen peroxide; acetic acid / dichloromethane / 0.33 h / 35 °C

3.1: caesium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 12 h / Reflux; Inert atmosphere

4.1: manganese(IV) oxide / 1,4-dioxane / 3 h / 60 °C

5.1: 1,4-dioxane / 36 h

6.1: sodium tris(acetoxy)borohydride / dichloromethane / 2 h / 20 °C

7.1: diphenylphosphoranyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 3 h / Reflux

8.1: hydrogen; palladium 10% on activated carbon / ethanol / 20 °C / 760.05 Torr

9.1: tetraethoxy orthosilicate / 3 h / Reflux

10.1: N,N-dimethyl-formamide / 140 °C / Inert atmosphere

With hydrogenchloride; manganese(IV) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetraethoxy orthosilicate; palladium 10% on activated carbon; diphenylphosphoranyl azide; hydrogen; dihydrogen peroxide; sodium tris(acetoxy)borohydride; caesium carbonate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmcl.2013.03.062