5,7-diphenyl-5H-dibenzazepine

Base Information

• Chemical Name: 5,7-diphenyl-5H-dibenzazepine
• CAS No.: 106569-03-3
• Molecular Formula: C₂₆H₁₉N
• Molecular Weight: 345.444
• Mol file: 106569-03-3.mol

Synonyms:5,7-diphenyl-5H-dibenzazepine

Chemical Property of 5,7-diphenyl-5H-dibenzazepine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7-diphenyl-5H-dibenzazepine

There total 5 articles about 5,7-diphenyl-5H-dibenzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

dibenzothiophene sulfone (1016-05-3) + N-benzylidene benzylamine (780-25-6) → 5,7-diphenyl-5H-dibenzazepine (106569-03-3)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; at 40 ℃; for 15h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere;

DOI:10.1002/hlca.202100195

Reference yield:

[2'-(Amino-phenyl-methyl)-biphenyl-2-yl]-phenyl-methanone → 5,7-diphenyl-5H-dibenzazepine (106569-03-3)

Guidance literature:

With toluene-4-sulfonic acid; In acetone; for 10h; Yield given; Heating;

DOI:10.1021/jo00380a010

Reference yield:

<2'-(2-phenyl-1,3-dioxolan-2-yl)<1,1'-biphenyl>-2-yl>phenylmethanone oxime (106568-98-3,106568-99-4) → 5,7-diphenyl-5H-dibenzazepine (106569-03-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Zn, concd. NH₃, ammonium aceatate / Heating

2: aq. 4-toluenesulfonic acid / acetone / 10 h / Heating

With ammonium hydroxide; ammonium acetate; toluene-4-sulfonic acid; zinc; In acetone;

DOI:10.1021/jo00380a010

upstream raw materials:

<2'-(2-phenyl-1,3-dioxolan-2-yl)<1,1'-biphenyl>-2-yl>phenylmethanone oxime

dibenzothiophene sulfone

N-benzylidene benzylamine

benzylamine

Downstream raw materials:

5-deuterio-5,7-diphenyldibenzazepine

5,7-diphenyldibenzazepin-5-ol