N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

Base Information

Chemical Name:N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide
CAS No.:1246368-12-6
Molecular Formula:C₂₂H₂₃Cl₂N₃O
Molecular Weight:416.35
Hs Code.:

Synonyms:N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

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Technology Process of N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

There total 1 articles about N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1204293-71-9
3-tert-butyl-N-(4-chlorobenzyl)-1-phenyl-1H-pyrazol-5-amine

: 79-04-9
chloroacetyl chloride

: 1246368-12-6
N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 10h; Cooling with ice; Inert atmosphere;
DOI:10.1107/S0108270110006244

Reference yield: 92.0%

: 1246368-12-6
N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

: 140-89-6
potassium ethyl xanthogenate

: 1318763-17-5
C₂₅H₂₈ClN₃O₂S₂

Guidance literature:: In acetonitrile; at 20 ℃; Darkness;
DOI:10.1016/j.tetlet.2011.05.105

Reference yield:

: 1246368-12-6
N-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-2-chloro-N-(4-chlorobenzyl)acetamide

: 1318763-26-6
C₂₂H₂₂ClN₃O

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 20 °C / Darkness

2: dilauryl peroxide / 1,2-dichloro-ethane / Inert atmosphere; Reflux

With dilauryl peroxide; In 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/j.tetlet.2011.05.105