C₃₉H₅₄O₁₁Si

Base Information

• Chemical Name: C₃₉H₅₄O₁₁Si
• CAS No.: 160582-78-5
• Molecular Formula: C₃₉H₅₄O₁₁Si
• Molecular Weight: 726.937
• Mol file: 160582-78-5.mol

Synonyms:C₃₉H₅₄O₁₁Si

Chemical Property of C₃₉H₅₄O₁₁Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₃₉H₅₄O₁₁Si

There total 5 articles about C₃₉H₅₄O₁₁Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

triethylsilyl chloride (994-30-9) + C33H40O11 (1045726-80-4) → C39H54O11Si (160582-78-5)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1021/jo00100a011

Reference yield:

7,13-O,O-Bis(triethylsilyl)baccatin III (150541-99-4) → C39H54O11Si (160582-78-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / imidazole / dimethylformamide / 0 °C

2: 66 percent / Red-Al / tetrahydrofuran / 0 °C

3: 75 percent / LHMDS / tetrahydrofuran / 0 °C

4: pyridine, 48percent HF / acetonitrile / 5 °C

5: 68 percent / imidazole / dimethylformamide / 0 °C

With pyridine; 1H-imidazole; hydrogen fluoride; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo00100a011

Reference yield:

1-dimethylsilyl-4-deacetyl-7,13-bis(triethylsilane)baccatin III (160582-75-2) → C39H54O11Si (160582-78-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 75 percent / LHMDS / tetrahydrofuran / 0 °C

2: pyridine, 48percent HF / acetonitrile / 5 °C

3: 68 percent / imidazole / dimethylformamide / 0 °C

With pyridine; 1H-imidazole; hydrogen fluoride; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo00100a011

upstream raw materials:

triethylsilyl chloride

C₃₃H₄₀O₁₁

7,13-O,O-Bis(triethylsilyl)baccatin III

1-dimethylsilyl-4-deacetyl-7,13-bis(triethylsilane)baccatin III

Downstream raw materials:

C₆₁H₈₁NO₁₄Si₂

Refernces