1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

Base Information

Chemical Name:1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt
CAS No.:1001413-86-0
Molecular Formula:C₂HF₃O₂*C₁₉H₁₄BrF₂N₃O₂
Molecular Weight:548.264
Hs Code.:

Synonyms:1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

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Chemical Property of 1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

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Technology Process of 1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

There total 5 articles about 1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1001413-01-9
1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid

: 188637-63-0
(6-bromopyridin-2-yl)methanamine

: 1001413-86-0
1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 1001414-50-1
C₁₄H₁₁F₂NO₃

: 1001413-86-0
1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / methanol / 60 °C

2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C

With sodium hydroxide; water; N-ethyl-N,N-diisopropylamine; HATU; In methanol; N,N-dimethyl-formamide;

Reference yield:

: 1001412-63-0
C₁₅H₁₃F₂NO₃

: 1001413-86-0
1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (6-bromo-pyridin-2-ylmethyl)-amide trifluoroacetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / 60 °C

2: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 20 °C

With sodium hydroxide; water; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide;