2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Base Information

Chemical Name:2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol
CAS No.:134098-64-9
Molecular Formula:C₁₉H₃₄O₂Si
Molecular Weight:322.563
Hs Code.:

Synonyms:2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Suppliers and Price of 2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

There total 6 articles about 2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 129967-42-6
2‐(3‐hydroxy‐1,1‐dimethylpropyl)‐3,5‐dimethylphenol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 134098-64-9
2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Guidance literature:: With triethylamine; In dichloromethane; for 24h; Ambient temperature;
DOI:10.1021/jo961778z

Reference yield:

: 924-50-5
Methyl 3,3-dimethylacrylate

: 134098-64-9
2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / benzene / 4 h / Reflux

2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Inert atmosphere

3: dmap / tetrahydrofuran / 14 h / Cooling with ice

With dmap; lithium aluminium tetrahydride; sulfuric acid; In tetrahydrofuran; benzene;
DOI:10.1039/b9nj00776h

Reference yield:

: 40662-14-4
4,4,5,7-tetramethyl-3,4-dihydrocoumarin

: 134098-64-9
2‐{3‐[(O‐tert‐butyldimethylsilyl)hydroxy]‐1,1‐dimethylpropyl}‐3,5‐dimethylphenol

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / Inert atmosphere

2: dmap / tetrahydrofuran / 14 h / Cooling with ice

With dmap; lithium aluminium tetrahydride; In tetrahydrofuran;
DOI:10.1039/b9nj00776h