methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

Base Information

Chemical Name:methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate
CAS No.:1235467-49-8
Molecular Formula:C₂₇H₂₄N₂O₄
Molecular Weight:440.499
Hs Code.:

Synonyms:methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

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Technology Process of methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

There total 1 articles about methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1235467-48-7
methyl 3-amino-2-(4-(benzyloxy)-phenyl)-6-bromoisonicotinate

: 5720-07-0
4-methoxyphenylboronic acid

: 1235467-49-8
methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

Guidance literature:: With potassium phosphate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; In tetrahydrofuran; Inert atmosphere; Reflux;

Reference yield:

: 1235467-49-8
methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate

: 1235467-50-1
methyl 3-azido-2-(4-hydroxyphenyl)-6-(4-methoxyphenyl)-isonicotinate

: 1235467-51-2
methyl 3-azido-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)isonicotinate

Guidance literature:: methyl 3-amino-2-(4-(benzyloxy)phenyl)-6-(4-methoxyphenyl)-isonicotinate; With sodium nitrite; In trifluoroacetic acid; for 0.5h; Cooling with ice;

With sodium azide; In diethyl ether; trifluoroacetic acid; for 0.5h; Cooling with ice;