(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Base Information

Chemical Name:(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione
CAS No.:1203835-05-5
Molecular Formula:C₂₁H₂₄N₂O₆S
Molecular Weight:432.497
Hs Code.:

Synonyms:(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Suppliers and Price of (R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of (R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of (R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

There total 9 articles about (R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 1092690-94-2
(R)-2-(N-(1-(benzyloxyamino)-3-methyl-1-oxobutan-2-yl)-4-methoxyphenylsulfonamido)acetic acid

: 1203835-05-5
(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Guidance literature:: With 4-methyl-morpholine; chloroformic acid ethyl ester; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1021/jm200593b

Reference yield:

: 1092690-91-9
N-(4-methoxybenzenesulfonyl)-N-tert-butoxycarbonylmethyl-O-benzyl-D-valinehydroxamic acid

: 1203835-05-5
(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 20 °C

2: 4-methyl-morpholine; chloroformic acid ethyl ester / tetrahydrofuran / 1 h / 0 °C

With 4-methyl-morpholine; chloroformic acid ethyl ester; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm200593b

Reference yield:

: 1092690-88-4
N-(4-methoxybenzenesulfonyl)-N-tert-butoxycarbonylmethyl-D-valine

: 1203835-05-5
(R)-1-(benzyloxy)-3-isopropyl-4-(4-methoxyphenylsulfonyl)piperazine-2,6-dione

Guidance literature:: Multi-step reaction with 4 steps

1: 4-methyl-morpholine / tetrahydrofuran / 0 °C

2: methanol / 0 °C

3: trifluoroacetic acid / dichloromethane / 20 °C

4: 4-methyl-morpholine; chloroformic acid ethyl ester / tetrahydrofuran / 1 h / 0 °C

With 4-methyl-morpholine; chloroformic acid ethyl ester; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm200593b