Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

Base Information

Chemical Name:Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate
CAS No.:141672-16-4
Molecular Formula:C₃₂H₃₂N₂O₇
Molecular Weight:556.615
Hs Code.:

Synonyms:Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

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Technology Process of Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

There total 1 articles about Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 100-39-0
benzyl bromide

: 119706-40-0
methyl 5(S)-N-(benzyloxycarbonyl)amino-6-(indol-3-yl)-2-methoxycarbonyl-4-oxohexanoate

: 141672-16-4
Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

Guidance literature:: With sodium methylate; In 1,2-dimethoxyethane; Ambient temperature;
DOI:10.1016/S0040-4020(01)88534-3

Reference yield:

: 141672-16-4
Methyl 2-benzyl-5(S)-benzyloxycarbonylamino-2-methoxycarbonyl-6-(indole-3-yl)-4-oxohexanoate

: 136969-62-5
(3R,6S)-3-Benzyl-6-(1H-indol-3-ylmethyl)-2,5-dioxo-piperidine-3-carboxylic acid methyl ester

: 136969-63-6
(3S,6S)-3-Benzyl-6-(1H-indol-3-ylmethyl)-2,5-dioxo-piperidine-3-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 168h; under 1551.4 Torr; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1016/S0040-4020(01)88534-3