Pentanamide,2-(acetylamino)-4-methyl-, (2S)-

Base Information

Chemical Name:Pentanamide,2-(acetylamino)-4-methyl-, (2S)-
CAS No.:28529-34-2
Molecular Formula:C8H16N2O2
Molecular Weight:172.22
Hs Code.:2924199090
Mol file:28529-34-2.mol

Synonyms:Valeramide, 2-acetamido-4-methyl-, L- (8CI);N-Acetyl-L-leucinamide;N-Acetyl-L-leucine amide;Pentanamide,2-(acetylamino)-4-methyl-, (S)-;(S)-2-(Acetylamino)-4-methylpentanamide;

Suppliers and Price of Pentanamide,2-(acetylamino)-4-methyl-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Acetyl-L-leucine amide
5g
$ 212.00

Sigma-Aldrich
N-ACETYL-L-LEUCINAMIDE AldrichCPR
50MG
$ 144.00

Crysdot
Acetyl-L-leucineamide 95+%
100g
$ 548.00

Chem-Impex
Acetyl-L-leucineamide,≥99%(TLC) ≥99%(TLC)
5G
$ 66.28

Chem-Impex
Acetyl-L-leucine amide ≥ 99% (TLC)
1G
$ 15.50

Chem-Impex
Acetyl-L-leucineamide,≥99%(TLC) ≥99%(TLC)
10G
$ 121.14

Biosynth Carbosynth
Acetyl-L-leucine amide
10 g
$ 119.60

Biosynth Carbosynth
Acetyl-L-leucine amide
5 g
$ 74.80

Total 12 raw suppliers

Chemical Property of Pentanamide,2-(acetylamino)-4-methyl-, (2S)-

Chemical Property:

Vapor Pressure:2.16E-06mmHg at 25°C
Refractive Index:1.462
Boiling Point:393.2 °C at 760 mmHg
Flash Point:191.6 °C
PSA：72.19000
Density:1.024 g/cm³
LogP:1.11370
Storage Temp.:Store at RT.

Purity/Quality:

99% ^*data from raw suppliers

Acetyl-L-leucine amide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pentanamide,2-(acetylamino)-4-methyl-, (2S)-

There total 8 articles about Pentanamide,2-(acetylamino)-4-methyl-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 1188-21-2
N-Ac-Leu

: 28529-34-2
N-acetyl-L-leucine amide

Guidance literature:: N-Ac-Leu; With triethylamine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃; for 0.5h;

With ammonium hydroxide; In tetrahydrofuran; for 0.5h;
DOI:10.1021/acs.joc.8b03224

Reference yield:

: 13649-95-1
(S)-4-isobutyl-2-methyloxazol-5(4H)-one

: 28529-34-2
N-acetyl-L-leucine amide

Guidance literature:: With ammonia; In toluene; at 80 ℃; for 0.5h;
DOI:10.1021/ja00364a041

Reference yield:

: 61-90-5,21675-61-6,25248-98-0,70-45-1
L-leucine

: 28529-34-2
N-acetyl-L-leucine amide

Guidance literature:: Multi-step reaction with 3 steps

1: 99 percent / 4N NaOH / 1 h / 0 °C

2: 1.) isobutylchloroformate, N-ethylmorpholine, 2.) ammonia / 1.) -15 deg C, 5 min, 2.) -15 deg C, 30 min

3: 1.) 5percent Pd/C / 1.) 80percent glacial acetic acid, overnight, 2.) pyridine

With N-ethylmorpholine;; sodium hydroxide; palladium on activated charcoal; ammonia; isobutyl chloroformate;
DOI:10.1007/BF00648899