Technology Process of (4-Chloro-phenyl)-[1-[4-(2-phenyl-pyrimidin-4-yl)-phenyl]-meth-(E)-ylidene]-amine
There total 5 articles about (4-Chloro-phenyl)-[1-[4-(2-phenyl-pyrimidin-4-yl)-phenyl]-meth-(E)-ylidene]-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 65.8 percent / sodium methylate / ethanol / 4 h / Heating
2: 90.2 percent / phosphorus oxychloride, triethylamine / 10 - 100 deg C during 1 h, 100 - 105 deg C 1 h
3: 87.5 percent / hydrogen, sodium acetate / 5 percent Pd/C / ethanol / 0.28 h / Ambient temperature
4: 54.3 percent / N-bromosuccinimide, dibenzoylperoxide, α,α'-azoisobutyronitrile / CCl4 / 3 h / Heating; Irradiation
5: 76.9 percent / sodium, ethanol, 2-nitropropane / dimethylformamide / 2 h / 60 - 65 °C
6: 65.4 percent / boric acid / xylene / 3 h / Heating
With
N-Bromosuccinimide; ethanol; 2-nitropropane; azobisisobutyronitrile; hydrogen; sodium methylate; sodium acetate; boric acid; sodium; triethylamine; trichlorophosphate; dibenzoyl peroxide;
palladium on activated charcoal;
In
tetrachloromethane; ethanol; N,N-dimethyl-formamide; xylene;
DOI:10.1002/hlca.19810640114
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 90.2 percent / phosphorus oxychloride, triethylamine / 10 - 100 deg C during 1 h, 100 - 105 deg C 1 h
2: 87.5 percent / hydrogen, sodium acetate / 5 percent Pd/C / ethanol / 0.28 h / Ambient temperature
3: 54.3 percent / N-bromosuccinimide, dibenzoylperoxide, α,α'-azoisobutyronitrile / CCl4 / 3 h / Heating; Irradiation
4: 76.9 percent / sodium, ethanol, 2-nitropropane / dimethylformamide / 2 h / 60 - 65 °C
5: 65.4 percent / boric acid / xylene / 3 h / Heating
With
N-Bromosuccinimide; ethanol; 2-nitropropane; azobisisobutyronitrile; hydrogen; sodium acetate; boric acid; sodium; triethylamine; trichlorophosphate; dibenzoyl peroxide;
palladium on activated charcoal;
In
tetrachloromethane; ethanol; N,N-dimethyl-formamide; xylene;
DOI:10.1002/hlca.19810640114
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 87.5 percent / hydrogen, sodium acetate / 5 percent Pd/C / ethanol / 0.28 h / Ambient temperature
2: 54.3 percent / N-bromosuccinimide, dibenzoylperoxide, α,α'-azoisobutyronitrile / CCl4 / 3 h / Heating; Irradiation
3: 76.9 percent / sodium, ethanol, 2-nitropropane / dimethylformamide / 2 h / 60 - 65 °C
4: 65.4 percent / boric acid / xylene / 3 h / Heating
With
N-Bromosuccinimide; ethanol; 2-nitropropane; azobisisobutyronitrile; hydrogen; sodium acetate; boric acid; sodium; dibenzoyl peroxide;
palladium on activated charcoal;
In
tetrachloromethane; ethanol; N,N-dimethyl-formamide; xylene;
DOI:10.1002/hlca.19810640114
