4-t-Butyl-1,2-phenylendioxydiacetonitril

Base Information

• Chemical Name: 4-t-Butyl-1,2-phenylendioxydiacetonitril
• CAS No.: 58774-64-4
• Molecular Formula: C₁₄H₁₆N₂O₂
• Molecular Weight: 244.293
• Mol file: 58774-64-4.mol

Synonyms:4-t-Butyl-1,2-phenylendioxydiacetonitril

Chemical Property of 4-t-Butyl-1,2-phenylendioxydiacetonitril

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-t-Butyl-1,2-phenylendioxydiacetonitril

There total 1 articles about 4-t-Butyl-1,2-phenylendioxydiacetonitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-tert-Butylcatechol (98-29-3) + chloroacetonitrile (107-14-2) → 4-t-Butyl-1,2-phenylendioxydiacetonitril (58774-64-4)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; Heating;

DOI:10.1002/hlca.19750580605

Reference yield: 81.0%

4-t-Butyl-1,2-phenylendioxydiacetonitril (58774-64-4) → 2-[2-(2-aminoethoxy)-4-tert-butylphenoxy]ethanamine (904681-54-5)

Guidance literature:

4-t-Butyl-1,2-phenylendioxydiacetonitril; With dimethylsulfide borane complex; In tetrahydrofuran; for 4h; Heating;

With hydrogenchloride; for 0.333333h; Further stages.; Heating;

DOI:10.1002/chem.200501409

Reference yield:

4-t-Butyl-1,2-phenylendioxydiacetonitril (58774-64-4) → 4-tert-Butyl-1,2-cyclohexandioxydiessigsaeure (58774-66-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. KOH / methanol

2: H₂, NaOAc / Rh-C / acetic acid / 27 °C / 1618.1 Torr

With potassium hydroxide; hydrogen; sodium acetate; Rh on carbon; In methanol; acetic acid;

DOI:10.1002/hlca.19750580605

upstream raw materials:

4-tert-Butylcatechol

chloroacetonitrile

Downstream raw materials:

4-t-Butyl-1,2-phenylendioxydiessigsaeure

2-[2-(2-aminoethoxy)-4-tert-butylphenoxy]ethanamine

4-tert-Butyl-1,2-cyclohexandioxydiessigsaeure

4-tert-Butyl-1,2-cyclohexandioxydiacetyldichlorid