Technology Process of C21H16O2
There total 3 articles about C21H16O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenyl phosphite; palladium diacetate; caesium carbonate;
In
1,4-dioxane;
at 140 ℃;
for 15h;
Inert atmosphere;
DOI:10.1021/ol2030923
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / tetrahydrofuran / 20 °C
2: triphenyl phosphite; palladium diacetate; caesium carbonate / 1,4-dioxane / 15 h / 140 °C / Inert atmosphere
With
triphenyl phosphite; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; palladium diacetate; caesium carbonate; diisopropylamine;
In
tetrahydrofuran; 1,4-dioxane;
1: Sonogashira-Hagihara cross coupling;
DOI:10.1021/ol2030923
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 60 °C
1.2: 0 - 20 °C
2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / tetrahydrofuran / 20 °C
3.1: triphenyl phosphite; palladium diacetate; caesium carbonate / 1,4-dioxane / 15 h / 140 °C / Inert atmosphere
With
triphenyl phosphite; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; palladium diacetate; potassium carbonate; caesium carbonate; diisopropylamine;
In
tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
2.1: Sonogashira-Hagihara cross coupling;
DOI:10.1021/ol2030923
