(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

Base Information

Chemical Name:(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate
CAS No.:1365438-34-1
Molecular Formula:C₂₆H₃₄NO₅P
Molecular Weight:471.533
Hs Code.:

Synonyms:(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

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Chemical Property of (S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

Chemical Property:

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Technology Process of (S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

There total 1 articles about (S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 119356-77-3
dapoxetine

: 229625-50-7
di-tert-butyl chloromethyl phosphate

: 1365438-34-1
(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

Guidance literature:: With sodium hydrogencarbonate; In acetonitrile; at 50 ℃; for 70h;

Reference yield: 96.0%

: 1365438-34-1
(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

: 1365438-37-4
(S)-(dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl hydrogen phosphate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 15h; Product distribution / selectivity;

Reference yield:

: 1365438-34-1
(S)-tert-butyl((dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl) phosphate

: (S)-(dimethyl(3-(naphthalen-1-yloxy)-1-phenylpropyl)ammonio)methyl phosphate sodium salt

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 15 h / 20 °C

2: sodium hydroxide / water / 5 h / 65 °C

With trifluoroacetic acid; sodium hydroxide; In dichloromethane; water;