Dapoxetine

Base Information Edit

Chemical Name:Dapoxetine
CAS No.:119356-77-3
Molecular Formula:C₂₁H₂₃NO
Molecular Weight:305.42
Hs Code.:2922199090
European Community (EC) Number:640-411-8
UNII:GB2433A4M3
DSSTox Substance ID:DTXSID0057627
Nikkaji Number:J561.856H
Wikipedia:Dapoxetine
Wikidata:Q424965
NCI Thesaurus Code:C75168
Pharos Ligand ID:A646T4ZB8UNK
Metabolomics Workbench ID:149314
ChEMBL ID:CHEMBL2110900
Mol file:119356-77-3.mol

Synonyms:dapoxetine;dapoxetine hydrochloride;LY 210448;LY-210448;N,N-dimethyl-alpha-(2-(1-naphthalenyloxy)ethyl)benzenemethanamine;Priligy

Suppliers and Price of Dapoxetine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dapoxetine hydrochloride
10mg
$ 366.00

TRC
Dapoxetine
1mg
$ 45.00

Tocris
Dapoxetine Hydrochloride ≥99%(HPLC)
50
$ 373.00

Sigma-Aldrich
Dapoxetine hydrochloride ≥98% (HPLC)
10 mg
$ 98.60

Sigma-Aldrich
Dapoxetine hydrochloride ≥98% (HPLC)
50 mg
$ 387.00

Labseeker
S-(+)-N,N-Dimethyl-a-[2-(naphthalenyloxy)ethyl]benzenemethanaminehydrochloride 98
500g
$ 892.00

Crysdot
Dapoxetine 95+%
5g
$ 65.00

Crysdot
Dapoxetine 95+%
25g
$ 215.00

Chemcia Scientific
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine ＞97%
5 G
$ 395.00

AvaChem
Dapoxetine
100mg
$ 95.00

Total 208 raw suppliers

Chemical Property of Dapoxetine Edit

Chemical Property:

Appearance/Colour:White to off-white crystalline powder
Vapor Pressure:1.91E-08mmHg at 25°C
Refractive Index:1.607
Boiling Point:454.4 °C at 760 mmHg
PKA:8.38±0.50(Predicted)
Flash Point:132.6 °C
PSA：12.47000
Density:1.081 g/cm³
LogP:4.91160
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:305.177964357
Heavy Atom Count:23
Complexity:337

Purity/Quality:

99%, ^*data from raw suppliers

Dapoxetine hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN(C)C(CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3
Isomeric SMILES:CN(C)[C@@H](CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3
Recent ClinicalTrials:Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile Dysfunction
Recent EU Clinical Trials:A Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group,
Uses Antidepressant. Dapoxetine-d7 Hydrochloride is a Labelled Dapoxetine (D185700). A selective serotonin reuptake inhibitor (SSRI).
Clinical Use Dapoxetine is a selective serotonin re-uptake inhibitor (SSRI) which has been approved in Finland and Sweden for the treatment of premature ejaculation.Dapoxetine was discovered and developed by Lilly and was licensed to Alza, a wholly-owned subsidiary of Johnson & Johnson.

Technology Process of Dapoxetine

There total 72 articles about Dapoxetine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.2%