(R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate

Base Information

Chemical Name:(R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate
CAS No.:1240893-64-4
Molecular Formula:C₃₂H₄₅NO₇SSi
Molecular Weight:615.863
Hs Code.:

Synonyms:(R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate

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Technology Process of (R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate

There total 1 articles about (R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1240893-59-7
(4S,5S)-4-(benzyloxymethyl)-5-((R)-1-hydroxy-3-(triisopropylsilyl)prop-2-ynyl)-3-(4-methoxybenzyl)oxazolidin-2-one

: 124-63-0
methanesulfonyl chloride

: 1240893-64-4
(R)-1-((4S,5S)-4-(benzyloxymethyl)-3-(4-methoxybenzyl)-2-oxooxazolidin-5-yl)-3-(triisopropylsilyl)prop-2-ynyl methanesulfonate

Guidance literature:: (4S,5S)-4-(benzyloxymethyl)-5-((R)-1-hydroxy-3-(triisopropylsilyl)prop-2-ynyl)-3-(4-methoxybenzyl)oxazolidin-2-one; With triethylamine; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

methanesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; for 1.5h; Inert atmosphere;
DOI:10.1039/c004218h