Technology Process of dimethyl 4,4'-((2,5-dibromo-1,4-phenylene)bisoxy)dibutanoate
There total 1 articles about dimethyl 4,4'-((2,5-dibromo-1,4-phenylene)bisoxy)dibutanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate; potassium iodide;
In
N,N-dimethyl-formamide;
for 1h;
DOI:10.1021/ma200296t
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine;
In
N,N-dimethyl-formamide;
at 60 ℃;
for 72h;
DOI:10.1021/ma200296t
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine / N,N-dimethyl-formamide / 72 h / 60 °C
2.1: sodium hydroxide / tetrahydrofuran; methanol / 16 h / 20 °C
2.2: pH 2
3.1: dmap; diisopropyl-carbodiimide / dichloromethane / 2 h / 20 °C
4.1: dmap; diisopropyl-carbodiimide / dichloromethane / 4 h / 20 °C
5.1: tetrabutyl ammonium fluoride; diisopropyl-carbodiimide / tetrahydrofuran / 0.25 h / Cooling with ice
With
dmap; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine; sodium hydroxide; diisopropyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
1.1: Sonogashira coupling;
DOI:10.1021/ma200296t
