1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

Base Information

Chemical Name:1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole
CAS No.:1363375-68-1
Molecular Formula:C₂₇H₃₃NO₅S
Molecular Weight:483.629
Hs Code.:

Synonyms:1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

Suppliers and Price of 1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of 1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

There total 2 articles about 1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 17739-45-6,59146-56-4
2-(2-bromoethoxy)tetrahydropyran

: [3-(2-ethoxyethyl)-2-methyl-5-(4-methylsulfonyl)phenyl-1-phenyl]-1H-pyrrole

: 1363375-68-1
1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

Guidance literature:: With sodium hydroxide; tetrabutylammomium bromide; at 0 - 70 ℃;

Reference yield: 79.0%

: 17739-45-6,59146-56-4
2-(2-bromoethoxy)tetrahydropyran

: 1005451-94-4
3-(2-hydroxyethyl)-2-methyl-1-phenyl-5-[(4-methylsulfonyl)phenyl]-1H-pyrrole

: 1363375-68-1
1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

Guidance literature:: With tetrabutylammomium bromide; sodium hydroxide; In water; at 70 ℃; for 72h; Inert atmosphere;
DOI:10.1021/jm301370e

Reference yield: 83.0%

: 1363375-68-1
1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole

: 1363375-22-7
2-[2-[1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-1H-pyrrol-3-yl]ethoxy]ethanol

Guidance literature:: 1-phenyl-2-methyl-5-(4-methylsulphonylphenyl)-3-[2-(2-(tetrahydro-2H-pyran-2-yl)oxy)ethoxy]ethyl-1H-pyrrole; With toluene-4-sulfonic acid; In methanol; at 55 ℃; for 1h;

With water; In deuteromethanol;