5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole

Base Information

Chemical Name:5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole
CAS No.:113700-23-5
Molecular Formula:C11H12 F N
Molecular Weight:177.221
Hs Code.:
DSSTox Substance ID:DTXSID70553018
Wikidata:Q82433487
Mol file:113700-23-5.mol

Synonyms:113700-23-5;5-[(4-FLUOROPHENYL)METHYL]-3,4-DIHYDRO-2H-PYRROLE;5-(4-Fluorobenzyl)-3,4-dihydro-2H-pyrrole;2H-Pyrrole, 5-[(4-fluorophenyl)methyl]-3,4-dihydro-;2-(4-fluorobenzyl)-1-pyrroline;SCHEMBL6477196;DTXSID70553018;UWUCQSWOBYQGOX-UHFFFAOYSA-N;AKOS006306917;A921675;5-[(4-Fluorophenyl)methyl]-3 pound not4-dihydro-2H-pyrrole;|A-Amino-4 inverted exclamation mark -fluoroacetophenone hydrochloride

Suppliers and Price of 5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
5-[(4-FLUOROPHENYL)METHYL]-3,4-DIHYDRO-2H-PYRROLE 95%
1 g
$ 750.00

Crysdot
5-(4-Fluorobenzyl)-3,4-dihydro-2H-pyrrole 95+%
1g
$ 589.00

Chemenu
5-(4-fluorobenzyl)-3,4-dihydro-2H-pyrrole 95%
1g
$ 556.00

American Custom Chemicals Corporation
5-(4-FLUOROBENZYL)-3,4-DIHYDRO-2H-PYRROLE 95.00%
5MG
$ 498.64

Alichem
5-(4-Fluorobenzyl)-3,4-dihydro-2H-pyrrole
1g
$ 494.40

Total 11 raw suppliers

Chemical Property of 5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole

Chemical Property:

PSA：12.36000
LogP:2.03860
Storage Temp.:2-8°C
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:177.095377549
Heavy Atom Count:13
Complexity:192

Purity/Quality:

97% ^*data from raw suppliers

5-[(4-FLUOROPHENYL)METHYL]-3,4-DIHYDRO-2H-PYRROLE 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=NC1)CC2=CC=C(C=C2)F

Technology Process of 5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole

There total 6 articles about 5-[(4-Fluorophenyl)methyl]-3,4-dihydro-2H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.8%

: 628-20-6
4-Chlorobutyronitrile

: 459-46-1
4-Fluorobenzyl bromide

: 113700-23-5
5-(4-fluorobenzyl)-3,4-dihydro-2H-pyrrole

Guidance literature:: 4-Fluorobenzyl bromide; With magnesium; In diethyl ether; at 40 ℃; for 2h;

4-Chlorobutyronitrile; In diethyl ether;

In toluene; at 95 ℃; for 2h;

Reference yield:

: 34837-84-8
4-fluorobenzeneacetic acid methyl ester

: 113700-23-5
5-(4-fluorobenzyl)-3,4-dihydro-2H-pyrrole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / o-xylene / Reflux

2: borane-THF / ethanol / 4 h

3: sodium hydroxide / toluene / 24 h / Reflux

With borane-THF; potassium carbonate; sodium hydroxide; In ethanol; o-xylene; toluene;