1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene

Base Information

• Chemical Name: 1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene
• CAS No.: 1107508-41-7
• Molecular Formula: C₁₆H₂₂O₂S
• Molecular Weight: 278.415
• Mol file: 1107508-41-7.mol

Synonyms:1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene

Chemical Property of 1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene

There total 1 articles about 1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl magnesium iodide (917-64-6) + (2S,3R)-2,3-dimethyl-2-(phenylsulfonylmethyl)cyclohexanone (1107508-36-0) → 1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene (1107508-41-7)

Guidance literature:

methyl magnesium iodide; (2S,3R)-2,3-dimethyl-2-(phenylsulfonylmethyl)cyclohexanone; In diethyl ether; at 0 - 20 ℃; for 17h;

With formic acid; at 80 ℃; for 2h;

DOI:10.1016/j.tet.2008.10.081

Reference yield:

1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene (1107508-41-7) + 2-{[(2E,6E)-8-iodo-3,7-dimethylocta-2,6-dien-1-yl]oxy}tetrahydro-2H-pyran (180151-09-1) → C31H46O4S (1107508-43-9)

Guidance literature:

1-{[(1S,6R)-1,2,6-trimethylcyclohex-2-enyl]methylsulfonyl}benzene; With n-butyllithium; In tetrahydrofuran; at 0 - 50 ℃;

2-{[(2E,6E)-8-iodo-3,7-dimethylocta-2,6-dien-1-yl]oxy}tetrahydro-2H-pyran; In tetrahydrofuran; at 50 ℃; for 3h;

DOI:10.1016/j.tet.2008.10.081

upstream raw materials:

methyl magnesium iodide

(2S,3R)-2,3-dimethyl-2-(phenylsulfonylmethyl)cyclohexanone

Downstream raw materials:

C₃₁H₄₆O₄S