N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide

Base Information

• Chemical Name: N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide
• CAS No.: 1015065-54-9
• Molecular Formula: C₂₂H₁₈F₃NO
• Molecular Weight: 369.386
• Mol file: 1015065-54-9.mol

Synonyms:N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide

Chemical Property of N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide

There total 2 articles about N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 9.1%

N-((R)-1-naphthalen-1-yl-ethyl)-acrylamide (1095393-70-6) + (meta-(trifluoromethyl)phenyl)boronic acid (1423-26-3) → N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide (1015065-54-9)

Guidance literature:

With acetic acid; [2,2]bipyridinyl; palladium diacetate; at 40 ℃; for 72h; Product distribution / selectivity;

Reference yield:

3-(trifluoromethyl)styrene (402-24-4) + N-((R)-1-naphthalen-1-yl-ethyl)-acrylamide (1095393-70-6) → N-((R)-1-naphthalen-1-yl-ethyl)-3-(3-trifluoromethyl-phenyl)-acrylamide (1015065-54-9)

Guidance literature:

dichloro(tricyclohexylphosphino)(benzylidene)(1,3-dimesityl-4,5-dihydroimidazol-2-ylidene)ruthenium(III); In toluene; at 85 ℃; for 7h; Product distribution / selectivity;

upstream raw materials:

N-((R)-1-naphthalen-1-yl-ethyl)-acrylamide

(meta-(trifluoromethyl)phenyl)boronic acid

3-(trifluoromethyl)styrene