2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide

Base Information

• Chemical Name: 2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide
• CAS No.: 1228378-20-8
• Molecular Formula: C₁₆H₁₅ClN₄O₂
• Molecular Weight: 330.774
• Mol file: 1228378-20-8.mol

Synonyms:2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide

Chemical Property of 2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide

There total 1 articles about 2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H18ClNO5S → 2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide (1228378-20-8)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; Cooling with ice;

DOI:10.1021/ja1027327

Reference yield: 14.0%

2-azido-N-(2-chloro-5-methoxyphenyl)-N-methyl-2-phenylacetamide (1228378-20-8) → 6-chloro-9-methoxy-1-methyl-3-phenyl-1,4-diazaspiro[4.5]deca-3,6,9-triene-2,8-dione (1228378-54-8) + 2-chloro-5-methoxyaniline (2401-24-3) + N?methyl?2?oxo?2?phenylacetamide (83490-71-5)

Guidance literature:

With phosphate potassium salt; oxygen; copper diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 10h; under 760.051 Torr;

DOI:10.1021/ja1027327

Downstream raw materials:

6-chloro-9-methoxy-1-methyl-3-phenyl-1,4-diazaspiro[4.5]deca-3,6,9-triene-2,8-dione

2-chloro-5-methoxyaniline

N?methyl?2?oxo?2?phenylacetamide