(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Base Information

Chemical Name:(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate
CAS No.:1373395-14-2
Molecular Formula:C₂₃H₂₀N₂O₃
Molecular Weight:372.423
Hs Code.:

Synonyms:(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Suppliers and Price of (2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

There total 4 articles about (2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 2227-57-8
3-(4-methoxyphenyl)propynoic acid

: 675123-18-9
1-(1-benzyl-1H-imidazol-4-yl)propen-3-ol

: 1373395-14-2
(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Guidance literature:: With dmap; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide; In dichloromethane; at -78 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol300704w

Reference yield:

: 37614-59-8
4-(4-methoxyphenyl)prop-2-yn-1-ol

: 1373395-14-2
(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Guidance literature:: Multi-step reaction with 3 steps

1: manganese(IV) oxide / dichloromethane / 45 °C

2: sodium dihydrogen phosphate monohydrate; cyclohexene / water; tert-butyl alcohol / 10 h / 0 - 20 °C

3: dmap; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

With dmap; manganese(IV) oxide; sodium dihydrogen phosphate monohydrate; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide; cyclohexene; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1021/ol300704w

Reference yield:

: 90696-21-2
3-(4-methoxyphenyl)propynal

: 1373395-14-2
(2E)-3-(1-benzyl-1H-imidazol-4-yl)prop-2-enyl 3-(4-methoxyphenyl)propynoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium dihydrogen phosphate monohydrate; cyclohexene / water; tert-butyl alcohol / 10 h / 0 - 20 °C

2: dmap; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

With dmap; sodium dihydrogen phosphate monohydrate; camphor-10-sulfonic acid; dicyclohexyl-carbodiimide; cyclohexene; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1021/ol300704w