(2S,4S)-2,4-dimethyl-4-phenyloxolane

Base Information

Chemical Name:(2S,4S)-2,4-dimethyl-4-phenyloxolane
CAS No.:99343-90-5
Molecular Formula:C₁₂H₁₆O
Molecular Weight:176.258
Hs Code.:
Nikkaji Number:J1.549.125F
Mol file:99343-90-5.mol

Synonyms:

Suppliers and Price of (2S,4S)-2,4-dimethyl-4-phenyloxolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of (2S,4S)-2,4-dimethyl-4-phenyloxolane

Chemical Property:

Boiling Point:248.7°Cat760mmHg
Flash Point:99.9°C
PSA：9.23000
Density:0.966g/cm³
LogP:2.75310
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:176.120115130
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 94%~99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CC(CO1)(C)C2=CC=CC=C2
Isomeric SMILES:C[C@H]1C[C@@](CO1)(C)C2=CC=CC=C2

Technology Process of (2S,4S)-2,4-dimethyl-4-phenyloxolane

There total 29 articles about (2S,4S)-2,4-dimethyl-4-phenyloxolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34713-70-7
2-Phenylpropanal

: 82461-14-1,99343-90-5,99343-91-6
2.4-dimethyl-4-phenyl-tetrahydrofuran

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / p-toluenesulphonic acid monohydrate / benzene / Heating

2: 88 percent / Pd(PPh₃), CF₃COOH / benzene / 20 h / 50 °C / other allylenamines; var. temperatures, reagents, and solvents

3: 2 N HCl / benzene / 1 h / Ambient temperature

4: 90 percent / LiAlH₄ / diethyl ether

5: 1.) mercuric acetate, 2.) NaBH₄, 3 M NaOH / 1.) THF/H₂O, 15 h, 2.)

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; Pd(PPh₃); mercury(II) diacetate; toluene-4-sulfonic acid; trifluoroacetic acid; In diethyl ether; benzene;
DOI:10.1021/jo00254a013

Reference yield:

: 24401-39-6
2-methyl-2-phenyl-pentenal

: 82461-14-1,99343-90-5,99343-91-6
2.4-dimethyl-4-phenyl-tetrahydrofuran

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / LiAlH₄ / diethyl ether

2: 1.) mercuric acetate, 2.) NaBH₄, 3 M NaOH / 1.) THF/H₂O, 15 h, 2.)

With sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; mercury(II) diacetate; In diethyl ether;
DOI:10.1021/jo00254a013

Reference yield:

: 100747-85-1
N-phenyl-2-methyl-2-phenyl-4-pentenylideneamine

: 82461-14-1,99343-90-5,99343-91-6
2.4-dimethyl-4-phenyl-tetrahydrofuran

Guidance literature:: Multi-step reaction with 3 steps

1: 2 N HCl / benzene / 1 h / Ambient temperature

2: 90 percent / LiAlH₄ / diethyl ether

3: 1.) mercuric acetate, 2.) NaBH₄, 3 M NaOH / 1.) THF/H₂O, 15 h, 2.)

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; mercury(II) diacetate; In diethyl ether; benzene;
DOI:10.1021/jo00254a013